The Klein lab at The Ohio State University acknowledges the Shawnee, Miami, Lenape, and Wyandotte peoples as the traditional land caretakers of central Ohio and we are grateful to have the opportunity to work in this place. As a land grant institution, we pay our respects to ancestors, elders, and relatives/relations past, present and emerging.
Omics is the collective name for a number of new fields of research, usually including genomics, transcriptomics, proteomics, metabolomics, and lipidomics. All of these various approaches have in common that they are based on analytical chemistry, generate large amounts of data, and (therefore) require computational data analysis. Omics techniques allow unprecedented insights into the molecular processes happening in living beings, and have sparked hopes of better understanding and treating modern-day diseases by revealing the disbalances causing these diseases.
The Klein Omics Lab
The Klein Omics Lab is working on integrating data from multiple Omics approaches to better understand human and animal disease and ultimately positively impacting our communities. The Klein Omics Lab research is backed by over a decade of successfully studying products of metabolism (metabolomics and lipidomics).
Metabolomics and Lipidomics
Metabolomics studies the entirety of small molecule metabolites and lipids (this variety of metabolomics is sometimes referred to as Lipidomics). Often, these approaches are used to identify correlations to health status and to predict disease onset. The development of metabolomics was sparked by improvements of analytical techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy as well as the rise of computational methods dealing with high-dimensional data. Metabolomics offers new, data-driven approaches applicable to any field dealing with living organisms and often provides stunning and unexpected new insights off the beaten track.